DTAmetasa is an Rshiny application aiming to assist users conducting meta-analysis of diagnostic test accuracy.
(For more detailed information about meta-analysis of diagnostic test accuracy, please refer to the Cochrane Screening and Diagnostic Tests Methods Group.)
DTAmetasa provides the following functionalities:
Summary descriptive statistics of multiple diagnostic studies with data of true positive, false positive, true negative, false negative. Note that, only data of sensitivities or specificities extracted from the published diagnostic studies CANNOT be analyzed.
Meta-analysis of diagnostic test accuracy with results of the difference estimates of summary operating receiver characteristics (SROC) curves and the area under the curves (SAUC).
Detection of publication bias in meta-analysis using funnel plot and the trim-and-fill method.
Adjustment of publication bias by the likelihood-based sensitivity analysis method. Note that this method is specific to the estimates by the bivariate normal model.
We suggest users prepare their data in CSV format or text format
The column names of data MUST BE TP, FN, FP, TN, indicating true positive, false negative, false positive, and true negative, respectively. The order of the columns does not matter. We present an example data in the first panel for reference.
Mizutani, S., Zhou, Y., Tian, Y.-S., Takagi, T., Ohkubo, T., & Hattori, S. (2023). DTAmetasa : An R shiny application for meta‐analysis of diagnostic test accuracy and sensitivity analysis of publication bias. Research Synthesis Methods, 14(6), 916–925. (https://doi.org/10.1002/jrsm.1666)
All the results in this application can be reproduced by using the following R packages
mada: Meta-Analysis of Diagnostic Accuracy (https://CRAN.R-project.org/package=mada)
mvmeta: Multivariate and Univariate Meta-Analysis and Meta-Regression (https://CRAN.R-project.org/package=mvmeta)
metafor: Meta-Analysis Package for R (https://CRAN.R-project.org/package=metafor)
dtametasa: Sensitivity Analysis for Publication Bias in Meta-analysis of Diagnostic Test Accuracy (https://github.com/meta2020/dtametasa)
The help button in the top of each panel will provide some helps and notations
The panel of Wiki gives the detailed description of models
| Date (yyyy-mm-dd) | Version | Details |
|---|---|---|
| 2024-08-01 | 1.0.0 | We added the introduction page |
| 2023-06-30 | 0.9.1 Beta | We updated the followings: - Change the color of SROC plot in Meta-analysis to distinguish the results from different models; added the legends - Added the Feedback button - Added the Reporting issue button - Change the names of Help tab into Wiki tab - Added Release history in Wiki - Added button for taking the survey |
| 2023-02-01 | 0.9.0 Beta | First release |